Novel Rifamycin Analogs to Treat Multidrug-Resistant Tuberculosis

Amycolatopsis mediterranei, which makes rifamycin B, can be engineered to produce analogs that inhibit rifamycin-resistant strains of M. tuberculosis

Shannon Weiman

Allies and Adversaries: Roles of the Microbiome in Infectious Disease

Studying how nonnative pathogens and host-associated microbial communities interact help us better understand infectious diseases

Jessica Miles, Jonathan F. Holt, and Jo Handelsman

Challenges of Antibiotic Discovery

Antibiotic resistance and tolerance plus troubles with discovery platforms complicate efforts to identify useful antibacterial drug candidates

Kim Lewis